Point-to-Point

Istanbul to Lisbon Cruises

11 Cruises 2 Cruise Lines

Route Map

Price Drops & Deals

15.6% OFF

Southern Mediterranean Gems

Oceania Cruises
Oceania Sirena 39 nights Nov 12, 2026
$9,739 $8,219 Save $1,520
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3.3% OFF

Grand Mediterranean Explorer

Viking Ocean Cruises
Viking Mira 35 nights Mar 10, 2027
$21,125 $20,425 Save $700
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2.2% OFF

Iberia, the Mediterranean & Aegean

Viking Ocean Cruises
Viking Mira 28 nights Dec 8, 2027
$8,890 $8,690 Save $200
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1.8% OFF

Iberia, the Mediterranean & Aegean

Viking Ocean Cruises
Viking Mira 28 nights Jan 13, 2027
$11,080 $10,880 Save $200
View Deal
1.4% OFF

Grand Mediterranean Explorer

Viking Ocean Cruises
Viking Jupiter 35 nights Sep 18, 2027
$21,290 $20,990 Save $300
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Compare Cruise Lines

Cruise Line Cruises Ships From Duration Next Sailing
Viking Ocean Cruises 10 5 $8,890 28-35 nights Jan 13, 2027
Oceania Cruises 1 1 $13,619 39 nights Nov 12, 2026

All Cruises on This Route

Ports on This Route

Piraeus

Wander through the Acropolis to stand before the magnificent Parthenon overlooking Athens and the sparkling Aegean Sea.

Barcelona

Wander through whimsical architectural masterpieces and vibrant Gothic quarters where Gaudí's genius meets Mediterranean charm.

Çanakkale

Explore the ancient ruins of Troy, a UNESCO World Heritage Site where Homer's legendary Trojan War unfolded millennia ago.

Naples

Descend into the haunting ruins of Pompeii and uncover everyday life frozen in volcanic ash from nearly two millennia ago.

Cartagena

Wander through centuries-old Mediterranean architecture while savoring fresh seafood in charming plazas overlooking pristine beaches.

Civitavecchia

Wander through Rome's ancient Colosseum and Vatican treasures just an hour from the coast.

Rhodes

Wander the medieval streets of the Old Town and stand before the legendary Palace of the Grand Masters, where crusader history comes alive.

Livorno

Wander through the Renaissance masterpiece of Pisa's Leaning Tower, just 25 minutes away by train from this charming Tuscan port city.

Messina

Ascend the hilltop Sanctuary of Montalto for breathtaking views of the Strait of Messina and Sicily's dramatic coastline.

Cádiz

Wander the oldest continuously inhabited city in Western Europe where golden beaches meet centuries of Moorish architecture and sherry wine traditions.

Palma de Mallorca

Wander through the stunning Gothic cathedral rising from turquoise waters and explore centuries of Mediterranean charm in this vibrant island capital.

Heraklion (Iraklion), Crete

Wander through the legendary Palace of Knossos to discover Europe's oldest civilization and the mythical home of King Minos.

Sète

Stroll along picturesque canals lined with colorful fishing boats and waterfront restaurants in this charming Mediterranean port city.

Tangier

Wander through the exotic medina's labyrinthine souks and savor authentic Moroccan cuisine while gazing across the Strait of Gibraltar.

Kusadasi

Wander through the marble columns of Ephesus, one of antiquity's greatest cities, just steps away from your ship.

Málaga

Wander through whitewashed villages clinging to dramatic cliffs while sipping crisp mountain wines in Spain's legendary Andalusian heartland.

Marseille

Explore the otherworldly Calanques National Park where towering limestone cliffs plunge into turquoise Mediterranean waters perfect for swimming and kayaking.

Monte-Carlo

Ascend the opulent Casino Square to witness Belle Époque grandeur and world-class gaming in Europe's most glamorous playground.

Katakolon

Explore the ancient Olympic Stadium and Temple of Zeus where athletes competed over 2,000 years ago in this birthplace of the Olympic Games.

Corfu

Wander the enchanting Venetian Old Town with its pastel-colored buildings and dramatic fortress perched above turquoise Ionian waters.

Split

Explore the 1,700-year-old Roman palace of Diocletian, perfectly preserved within the medieval Old Town's winding stone streets.

Kotor

Navigate medieval stone streets and fortress walls rising dramatically from a fjord-like bay surrounded by towering mountains.

Bari

Wander through medieval alleyways to discover the stunning Basilica di San Nicola, where Bari's soul intertwines with centuries of Byzantine history and charm.

Crotone

Explore the stunning Castle of Crotone perched dramatically above the Ionian Sea with breathtaking Mediterranean views.

Dubrovnik

Wander the iconic limestone walls encircling the medieval Old Town while gazing over the sparkling Adriatic Sea below.

Sibenik

Explore the stunning Gothic Cathedral of St. James, a UNESCO treasure perched above medieval Sibenik's charming waterfront streets.

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