Roundtrip

San Diego, California South America Cruises

12 Cruises 1 Cruise Lines

Route Map

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Cruise Line Cruises Ships From Duration Next Sailing
Holland America Line 13 2 $1,729 12-30 nights Nov 19, 2026

All Cruises on This Route

Ports on This Route

Cabo San Lucas

Witness the dramatic clash of the Pacific Ocean and Sea of Cortez at El Arco, a stunning natural rock formation that defines Cabo's rugged coastal beauty.

La Paz

Dive into the stunning Sea of Cortez to swim alongside whale sharks, sea lions, and tropical fish in one of the world's most biodiverse marine sanctuaries.

Loreto

Dive into pristine waters to encounter whale sharks and colorful tropical fish in one of Mexico's most unspoiled marine paradises.

Mazatlán

Stroll the golden beaches of the Malecón while colonial architecture and fresh seafood markets reveal why locals call this Pacific gem their coastal paradise.

Puerto Vallarta

Wander through colorful colonial streets lined with galleries and shops, then relax on pristine beaches backed by lush tropical mountains.

Ensenada

Shop authentic Mexican crafts at colorful markets, sample fresh seafood, and hike to scenic coastal cliffs overlooking the Pacific Ocean.

Honolulu, Hawaii

Paddle through crystal-clear waters at Hanauma Bay to encounter sea turtles and tropical fish in a protected marine sanctuary.

Kahului-Maui, Hawaii

Dive into Molokini Crater's crystal-clear waters to witness Hawaii's most spectacular marine life and vibrant coral ecosystems.

Kailua-Kona, Hawaii

Snorkel pristine coral gardens teeming with tropical fish and encounter gentle sea turtles in crystalline Hawaiian waters.

Lihue, Kauai Island, Hawaii

Paddle through dramatic sea caves and emerald cliffs on the breathtaking Napali Coast by boat or helicopter.

Hilo, Hawaii

Witness the raw power of Kilauea volcano and explore lush tropical rainforests in Hawaii's most pristine natural wonder.

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